Sleep hormone melatonin

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The sleep hormone melatonin is listed as a new panacea in the US, where it is found in numerous nutritional supplements: it is not only intended to help sleep disorders, but also has a positive impact on the aging process of the cells, as well as on the cancer and cardiovascular system due to its antioxidant effect Illnesses take. In fact, the effect of melatonin has so far been insufficiently researched, which is why it may only be used as a sleep aid in Germany. Also about possible side effects of melatonin is not yet sufficiently known.

Effect of melatonin

Melatonin is a hormone that controls the human day-and-night cycle - the so-called circadian rhythm. It is made from serotonin in the pineal gland. In addition, it is also produced in other places in the body, for example in the digestive tract. However, melatonin from the pineal gland is responsible for controlling the day-night rhythm.

In the pineal gland, the hormone is released only in the dark - so we get tired in the evening. The level of melatonin in the blood rises slowly and reaches its peak in the middle of the night - between about two and three o'clock. In the early morning hours, the mirror then falls off again, because light inhibits production.

But melatonin not only regulates the sleep-wake cycle, but also many biological functions associated with it. These include, for example, kidney function and blood pressure. That the hormone can not only affect the sleep-wake cycle, but also other physical processes, should be observed before taking a melatonin drug.

Disorders of the melatonin household

Shift work or a time delay in long-distance travel can cause disturbances in the melatonin budget. By an additional intake of melatonin, however, these disorders are supposed to be able to be repaired: So should the hormone ensure that you can fall asleep faster in the evening in jetlag-related sleep disorders.

However, this effect of melatonin is still controversial: while the hormone in some studies had a positive effect on the sleep behavior, it showed no effect in other studies. Often, the effect occurred only after a few days of intake. Positive influence on the effect of melatonin should cross as many time zones as possible and west-east flights.

But not only for jet lag, but also for shiftwork, the additional intake to help the body to get used to the normal daily routine again. The same applies to blind people whose sleep-wake rhythm has decoupled from the day-night rhythm.

Melatonin and depression

Changes in the melatonin household occur particularly frequently in winter, as the level of the hormone is also increased during the day due to the low level of daylight. This can lead to sleep disorders, fatigue and winter depression. To prevent such symptoms, one should use the little daylight for walks. By daylight, the release of melatonin is more inhibited and the level in the blood drops. In case of severe symptoms you should consider a light therapy.

Melatonin as a sleeping aid

The older we get, the less melatonin our body produces. This fact suggests that age-related sleep disturbances are associated with the decrease in melatonin levels. That is why people sleeping over 55 years in Germany are admitted to sleep medication containing melatonin. Each tablet contains a dose of two milligrams.

The drug is suitable for the short-term treatment of sleep disorders due to poor sleep quality (primary sleep disorders). However, sleep disorders caused by a disease or certain medications can not be treated with melatonin. But the treatment of primary sleep disorders is also controversial, because in about half of the patients, the sleep aid has no effect.

Tip: If you suffer from sleep disorders, you should definitely take care to sleep in a darkened room so that the pineal gland can disperse as long as possible melatonin.

Dietary supplements

In recent years, melatonin has made a name for itself as a miracle cure, especially in the US, where it is contained in numerous nutritional supplements. Among other things, it should stop cell aging, burn fat, protect against hair loss and prevent or cure diseases such as AIDS, Alzheimer's and cancer.

In Germany, melatonin is classified as a drug and therefore not included in nutritional supplements. Appropriate dietary supplements can easily be ordered via the internet. However, it is difficult for the buyer to determine how high the quality of the offered product is and what risks it entails. Therefore, the purchase of melatonin via the Internet is strongly discouraged.

Antioxidant effect

That melatonin in the body has an antioxidant effect, is now considered scientifically proven: The hormone traps free radicals that damage the cells, and destroys them. Because it is both fat and water soluble unlike many other antioxidants, the hormone provides good all-round protection against free radicals.

The antioxidant activity of the hormone suggests that the aging process of the cells is related to the age-related release of melatonin. Whether this is indeed the case and whether the lower melatonin concentration is a consequence or cause of aging, but is not yet clear. Similarly, a link between the intake of melatonin and a slowing of the aging process is not scientifically proven.

Effect of melatonin is controversial

Due to its antioxidant properties, the hormone is not only thought to slow down the aging process, but also has a positive effect on the prevention and control of cancers and the prevention of cardiovascular disease. Whether melatonin can actually prevent such diseases is currently not scientifically proven.

The impact of melatonin on cancer has been studied in a number of studies - but with conflicting results. For example, while the hormone preserved healthy cells from chemotherapy damage in some tests, the hormone in another study also protected the cancer cells from dying. According to experts, there is currently no reason for cancer patients to take appropriate preparations.

Side effects of melatonin

For a short time - ie taken over a period of a maximum of two to three months - melatonin has hardly any side effects. So far, symptoms such as drowsiness and lack of concentration have been observed, as well as chest pain, dizziness, stomach or headache. Also, the natural sleep-wake cycle can be disturbed by the intake of melatonin. In contrast to a short-term dose, the risks and side effects of long-term use are currently completely unexplored.

For safety reasons, the use of melatonin should be avoided during pregnancy and lactation, as well as in severe allergies. If the hormone is taken together with anti-epileptic drugs, antidepressants (SSRIs) and antithrombotic agents, it may possibly lead to interactions between the various medications.

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